Description:

Systems Immunology and Infection Microbiology provides a large amount of biological system models, diagrams and flowcharts to illustrate the development procedure to understand the results of the systems immunology and infection microbiology. The results are not only remarkable, but also revolutionary in immunology and infection microbiology and can be also applied to systems drug design in infectious diseases.The book is divided into six parts. The first one discusses systems immunology; the second, systems infection microbiology; the third, systematic inflammation and immune responses in restoration and regeneration process; the forth introduces systems innate and adaptive immunity in infection process; systematic genetic and epigenetic pathogenic/defensive mechanism during bacterial infection on human cells is introduced in the fifth part; and the sixth and final part discusses systematic genetic and epigenetic pathogenic/defensive mechanism during the viral infection on human cells.This book provides a new big data-driven and systems-driven systems immunology and infection microbiology to researchers applying systems biology and bioinformatics in their works, and to several members of biomedical field who are interested to learn more about those approaches. Encompasses one applicable example in every chapter to illustrate the solution procedure from big data mining, network modelling, host/pathogen cross-talk detection, drug target identification and systems drug design Presents flowcharts to represent the development procedure of systematic immunology and infection in a very clear format Contains 100 colour diagrams to help readers understand the related biological networks, their corresponding mechanisms and significant network biomarkers for therapeutic drug design